Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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841
Tocris Bioscience™ JNJ 55511118
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective, high affinity negative modulator of AMPA receptors containing TARP-γ8
| CAS | 2036081-86-2 |
|---|---|
| Chemical Name or Material | 5-[2-Chloro-6-(trifluoromethoxy)phenyl]-1,3-dihydro-2H-benzimidazol-2-one |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C14H8ClF3N2O2 |
| Formula Weight | Observed MW: 328.67 |
| Assay Percent Range | >98% |
842
Tocris Bioscience™ Irbesartan
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent AT1 antagonist
843
Tocris Bioscience™ DSPE-PEG 2000 Maleimide
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PEGylated DSPE with a maleimide reactive group
844
Tocris Bioscience™ SMER 3
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CAS: 67200-34-4 Molecular Formula: C11H4N4O2
| CAS | 67200-34-4 |
|---|---|
| Molecular Formula | C11H4N4O2 |
845
Tocris Bioscience™ BC 11 hydrobromide
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CAS: 443776-49-6 Molecular Formula: C8H12BBrN2O2S
| CAS | 443776-49-6 |
|---|---|
| Molecular Formula | C8H12BBrN2O2S |
846
| CAS | 84687-43-4 |
|---|---|
| Molecular Formula | C41 H68 O14 |
847
Tocris Bioscience™ Sodium Cromoglicate
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Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
848
Tocris Bioscience™ PD 184352
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CAS: 212631-79-3 Molecular Formula: C17H14ClF2IN2O2
| CAS | 212631-79-3 |
|---|---|
| Molecular Formula | C17H14ClF2IN2O2 |
849
Tocris Bioscience™ CIMBA hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective G protein-coupled estrogen receptor (GPER) antagonist
850
Tocris Bioscience™ CITFA
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Potent G protein-coupled estrogen receptor (GPER) agonist
851
Tocris Bioscience™ GS 39783
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CAS: 39069-52-8 Molecular Formula: C15H23N5O2S
| CAS | 39069-52-8 |
|---|---|
| Molecular Formula | C15H23N5O2S |
852
Tocris Bioscience™ Tiotidine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 69014-14-8 Molecular Formula: C10H16N8S2
| CAS | 69014-14-8 |
|---|---|
| Molecular Formula | C10H16N8S2 |
853
Tocris Bioscience™ EM 12-FS
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Molecular glue; induces degradation of NQAT1
| Target | Molecular Glues |
|---|---|
| CAS | 2839138-44-0 |
| Purity | 0.95 |
| Chemical Name or Material | 3-[6-[(Fluorosulfonyl)oxy]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C13H11FN2O6S |
854
Tocris Bioscience™ TM2 TEAD inhibitor
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and reversible inhibitor of TEAD mediated Hippo/Yap signalling
| Target | YAP1 |
|---|---|
| CAS | 1008768-41-9 |
| Purity | 0.98 |
| Chemical Name or Material | 4-[3-(2-Cyclohexylethoxy)benzoyl]-N-phenyl-1-piperazinecarboxamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H33N3O3 |
855
Tocris Bioscience™ Isradipine
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CAS: 75695-93-1 Molecular Formula: C19H21N3O5
| CAS | 75695-93-1 |
|---|---|
| Molecular Formula | C19H21N3O5 |